Implementación de la relidad virtual en el ámbito de la recuperación funcional del sistema propioceptivo: rehabilitación con videojuegos comerciales

OBJETIVO: Evaluar la eficacia terapéutica y utilidad diagnóstica de Wii (Nintendo) y Kinect (Xbox 360),en las alteraciones del Sistema Propioceptivo. INTRODUCCIÓN: Emplear videojuegos en el terreno de la Rehabilitación,plantea una solución para ejercitarse en un ambiente divertido,competitivo y motivador,superando la monotonía de terapias clásicas. El entorno virtual supervisado, permite realizar actividades funcionales y alcanzar objetivos médicos, que de otro modo sería imposible. MATERIAL Y MÉTODO: Estudio transversal descriptivo (n=20).Se incluyeron pacientes con alteraciones del Sistema Propioceptivo secundarias a patologías neurológicas y del aparato locomotor.Se emplearon los dispositivos Wii,mediante Wii Balance Board,y Kinect,para el tratamiento y evaluación previa/posterior,en un protocolo establecido en tres fases. RESULTADOS: Mejoría significativa (p<0,05),de todos los pacientes, en la respuesta del Sistema Propioceptivo posterior al tratamiento.El análisis se elaboró mediante una batería de test biomecánicos,específica y reproducible,incluida en el videojuego Wii Fit Plus. CONCLUSIONES: Wii y Kinect son herramientas eficaces en la evaluación y tratamiento de las alteraciones del Sistema Propioceptivo.Departamento de Cirugía, Oftalmología, Otorrinolaringología y Fisioterapi

La industria a través de los mapas digitales: una investigación sobre el aprendizaje de la Geografía en secundaria

La irrupción de las tecnologías de la información y la comunicación en la sociedad actual ha generado la modernización de los procesos de enseñanza-aprendizaje en los centros educativos, prestando interés a metodologías activas, multiplicidad de recursos, contenidos interactivos, instrumentos de evaluación variados, relaciones en el aula y al alumno como centro del sistema, siempre actuando bajo la legitimidad del currículo. El presente estudio realiza un análisis cualitativo y cuantitativo acerca de la utilización de recursos TIC, en concreto herramientas SIG, en dos aulas de Geografía de 3º de ESO, mediante la realización de un proyecto de innovación relacionado con el aprendizaje basado en problemas. El trabajo se centra en la ubicación idónea de una instalación industrial en Aragón, teniendo en cuenta cuatro factores de localización preestablecidos, de forma que se pretende que los alumnos construyan su conocimiento geográfico a partir del uso de SIG y de la resolución de problemas sociales y espaciales, así como despertar en ellos motivación por la materia, autonomía, interpretación cartográfica, espíritu crítico o creatividad. Palabras clave: metodologías activas, recursos TIC, herramientas SIG, aprendizaje basado en problemas, factores de localización, conocimiento geográfico, interpretación cartográfica

Relationship between tillage management and DMPSA nitrification inhibitor efficiency

Agricultural sustainability is compromised by nitrogen (N) losses caused by soil microbial activity. Nitrous oxide (N2O) is a potent greenhouse gas (GHG) produced as consequence of nitrification and denitrification processes in soils. Nitrification inhibitors (NI) as 3,4-dimethylpyrazole-succinic acid (DMPSA) are useful tools to reduce these N losses from fertilization. The objective of this work was to test the efficiency of DMPSA in two different tillage management systems, conventional tillage (CT) and no-tillage (NT), in a winter wheat crop under Humid Mediterranean conditions. N fertilizer was applied as ammonium sulphate (AS) with or without DMPSA in a single or split application, including an unfertilized treatment. GHG fluxes N2O, CO2 and CH4) were measured by the closed chamber method. amoA and nosZl genes were quantified by qPCR as indicators of nitrifying and denitrifying populations. Nitrification was inhibited by DMPSA in both CT and NT, while the higher water filled pore space (WFPS) in NT promoted a better efficiency of DMPSA in this system. This higher efficiency might be due to a greater N2O reduction to N-2 as result of the nosZl gene induction. Consequently, DMPSA was able to reduce N2O emissions down to the unfertilized levels in NT. Provided that NT reduced CO2 emissions and maintained crop yield compared to CT, the application DMPSA under NT management is a promising strategy to increase agro-systems sustainability under Humid Mediterranean conditions. (C) 2019 The Author(s). Published by Elsevier B.V.This project was funded by de Spanish Government (AGL2015-64582-C3-2-R MINECO/FEDER and RTI2018-094623-B-C21 MCIU/AEI/FEDER, UE), by the Basque Government (IT-932-16) and by EuroChem Agro Iberia S.L.-UPV/EHU 2017.0016. Mario Corrochano-Monsalve held a grant from the Ministry of Economy and Business of the Spanish Government and Ximena Huerfano received a specialization fellowship for PhD researches from the UPV/EHU

Luminiscent and Magnetic Tb-MOF Flakes Deposited on Silica

The synthesis of a terbium-based 2D metal-organic framework (MOF), of formula [Tb(MeCOO)(PhCOO)2] (1), a crystalline material formed by neutral nanosheets held together by Van der Waals interactions, is presented. The material can be easily exfoliated by sonication and deposited onto different substrates. Uniform distributions of Tb-2D MOF flakes onto silicon were obtained by spin-coating. We report the luminescent and magnetic properties of the deposited flakes compared with those of the bulk. Complex 1 is luminescent in the visible and has a sizeable quantum yield of QY = 61% upon excitation at 280 nm. Photoluminescence measurements performed using a micro-Raman set up allowed us to characterize the luminescent spectra of individual flakes on silicon. Magnetization measurements of flakes-on-silicon with the applied magnetic field in-plane and out-of-plane display anisotropy. Ac susceptibility measurements show that 1 in bulk exhibits field-induced slow relaxation of the magnetization through two relaxation paths and the slowest one, with a relaxation time of tlf ⇡ 0.5 s, is assigned to a direct process mechanism. The reported exfoliation of lanthanide 2D-MOFs onto substrates is an attractive approach for the development of multifunctional materials and devices for different applications

Biochar reduces the efficiency of nitrification inhibitor 3,4-dimethylpyrazole phosphate (DMPP) mitigating N2O emissions

Among strategies suggested to decrease agricultural soil N2O losses, the use of nitrification inhibitors such as DMPP (3,4-dimethylpyrazole phosphate) has been proposed. However, the efficiency of DMPP might be affected by soil amendments, such as biochar, which has been shown to reduce N2O emissions. This study evaluated the synergic effect of a woody biochar applied with DMPP on soil N2O emissions. A incubation study was conducted with a silt loam soil and a biochar obtained from Pinus taeda at 500 degrees C. Two biochar rates (0 and 2% (w/w)) and three different nitrogen treatments (unfertilized, fertilized and fertilized + DMPP) were assayed under two contrasting soil water content levels (40% and 80% of water filled pore space (WFPS)) over a 163 day incubation period. Results showed that DMPP reduced N2O emissions by reducing ammonia-oxidizing bacteria (AOB) populations and promoting the last step of denitrification (measured by the ratio nosZI + nosZII/nirS + nirK genes). Biochar mitigated N2O emissions only at 40% WFPS due to a reduction in AOB population. However, when DMPP was applied to the biochar amended soil, a counteracting effect was observed, since the N2O mitigation induced by DMPP was lower than in control soil, demonstrating that this biochar diminishes the efficiency of the DMPP both at low and high soil water contents.This work was funded by the Spanish Government (AGL2015-64582-C3-2-R MINECO/FEDER), by the Basque Government (IT-932-16) and by the European Union (FACCE-CSA no 276610/MIT04-DESIGN-UPVASC, FACCE-CSA no 2814ERA01A and 2814ERA02A). This work is also supported by the USDA/NIFA Interagency Climate Change Grant Proposal number 2014-02114 [Project number 6657-12130-002-08I, Accession number 1003011] under the Multi-Partner Call on Agricultural Greenhouse Gas Research of the FACCE-Joint Program Initiative. Any opinions, findings, or recommendation expressed in this publication are those of the authors and do not necessarily reflect the view of the USDA. MLC was supported by a Ramon y Cajal contract from the Spanish Ministry of Economy and Competitiveness and thanks Fundacion Seneca for financing the project 19281/PI/14

El fenómeno del dopaje desde la perspectiva de las Ciencias Sociales Odile

En este libro se recoge una selección de las comunicaciones presentadas en el IV Congreso Internacional ‘Deporte, Dopaje y Sociedad’ que se celebró en Madrid del 26 de febrero al 1 de marzo de 2014 y que fue organizado conjuntamente por la Universidad Politécnica de Madrid y la Agencia Española de Protección de la Salud en el Deporte. Los textos están escritos en español, francés e inglés y abordan el estudio del fenómeno del dopaje desde el ámbito especifico de las Ciencias Humanas y Sociales a través de disciplinas como Historia, Derecho, Sociología, Psicología, Economía, Ciencias de la Información y otras disciplinas relacionadas

The Gaia mission

Gaia is a cornerstone mission in the science programme of the EuropeanSpace Agency (ESA). The spacecraft construction was approved in 2006, following a study in which the original interferometric concept was changed to a direct-imaging approach. Both the spacecraft and the payload were built by European industry. The involvement of the scientific community focusses on data processing for which the international Gaia Data Processing and Analysis Consortium (DPAC) was selected in 2007. Gaia was launched on 19 December 2013 and arrived at its operating point, the second Lagrange point of the Sun-Earth-Moon system, a few weeks later. The commissioning of the spacecraft and payload was completed on 19 July 2014. The nominal five-year mission started with four weeks of special, ecliptic-pole scanning and subsequently transferred into full-sky scanning mode. We recall the scientific goals of Gaia and give a description of the as-built spacecraft that is currently (mid-2016) being operated to achieve these goals. We pay special attention to the payload module, the performance of which is closely related to the scientific performance of the mission. We provide a summary of the commissioning activities and findings, followed by a description of the routine operational mode. We summarise scientific performance estimates on the basis of in-orbit operations. Several intermediate Gaia data releases are planned and the data can be retrieved from the Gaia Archive, which is available through the Gaia home page. http://www.cosmos.esa.int/gai

Luminescent and magnetic Tb-MOF flakes deposited on silicon

This article belongs to the Special Issue 2D Magnetic Molecular Materials.The synthesis of a terbium-based 2D metal–organic framework (MOF), of formula [Tb(MeCOO)(PhCOO)2] (1), a crystalline material formed by neutral nanosheets held together by Van der Waals interactions, is presented. The material can be easily exfoliated by sonication and deposited onto different substrates. Uniform distributions of Tb-2D MOF flakes onto silicon were obtained by spin-coating. We report the luminescent and magnetic properties of the deposited flakes compared with those of the bulk. Complex 1 is luminescent in the visible and has a sizeable quantum yield of QY = 61% upon excitation at 280 nm. Photoluminescence measurements performed using a micro-Raman set up allowed us to characterize the luminescent spectra of individual flakes on silicon. Magnetization measurements of flakes-on-silicon with the applied magnetic field in-plane and out-of-plane display anisotropy. Ac susceptibility measurements show that 1 in bulk exhibits field-induced slow relaxation of the magnetization through two relaxation paths and the slowest one, with a relaxation time of τlf ≈ 0.5 s, is assigned to a direct process mechanism. The reported exfoliation of lanthanide 2D-MOFs onto substrates is an attractive approach for the development of multifunctional materials and devices for different applications.This research was funded by the Spanish Ministry of Economy, Industry and Competitiveness (MINECO, Grant Nos. MAT2017-83468-R; PGC2018-098630-B-I00 (ECS)) and from the regional Government of Aragon (E12-20R RASMIA project).Peer reviewe

A Genome-Wide Association Study on Liver Stiffness Changes during Hepatitis C Virus Infection Cure

Liver stiffness (LS) at sustained virological response (SVR) after direct-acting antivirals (DAA)-based therapy is a predictor of liver events in hepatitis C virus (HCV)-infected patients. The study aim was to identify genetic factors associated with LS changes from the moment of starting anti-HCV therapy to SVR. This prospective study included HCV-infected patients from the GEHEP-011 cohort who achieved SVR with DAA-based therapy, with LS pre-treatment ≥ 9.5 kPa and LS measurement available at SVR. Plink and Magma software were used to carry out genome-wide single-nucleotide polymorphism (SNP)-based and gene-based association analyses, respectively. The ShinyGO application was used for exploring enrichment in Gene Ontology (GO) categories for biological processes. Overall, 242 patients were included. Median (quartile 1, quartile 3) LS values at pre-treatment and at SVR were 16.8 (12, 28) kPa and 12.0 (8.5, 19.3) kPa, respectively. Thirty-five SNPs and three genes reached suggestive association with LS changes from the moment of starting anti-HCV therapy to SVR. GO categories related to DNA packaging complex, DNA conformation change, chromosome organization and chromatin organization were significantly enriched. Our study reports possible genetic factors associated with LS changes during HCV-infection cure. In addition, our results suggest that processes related to DNA conformation are also involved in these changes.This work was supported by a grant from the Consejería de Salud de la Junta de An dalucía (project PI-0001/2017), and partially founded by the Instituto de Salud Carlos III (Projects PI16/01443 and PI19/01312), integrated in the national I+D+i 2013–2016, 2016–2019, and co-funded by the European Union (ERDF/ESF, “Investing in your future”), by the Spanish Network for AIDS investigation (RIS) (www.red.es/redes/inicio (accessed on 1 January 2021)) (RD16/0025/0040), as a part of the Nacional I+ D+I, ISCIII Subdirección General de Evaluación and the European Fund for Development of Regions (FEDER) and by GEHEP-SEIMC (GEHEP-011 project). J.A.P. has received a research extension grant from the Programa de Intensificación de la Actividad de Investigación del Servicio Nacional de Salud Carlos III (I3SNS). A.C.-G. has received a Río Hortega grant from the Instituto de Salud Carlos III (grant number CM19/00251). A.G.-S. is the recipient of a Miguel Servet Research Contract by Instituto de Salud Carlos III (CP18/00146). I.R. is the recipient of a P-FIS Research Contract by Instituto de Salud Carlos IIII (FI20/00215). A.Ruiz. is supported by national grants PI13/02434, PI16/01861 and PI19/01301. Acción Estratégica en Salud is integrated into the Spanish National R + D + I Plan and funded by ISCIII (Instituto de Salud Carlos III), Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER “Una manera de Hacer Europa”) and received support from the European Union/EFPIA Innovative Medicines Ini tiative Joint Undertaking ADAPTED and MOPEAD projects (Grants No. 115975 and 115985) and PREADAPT project (JPco-fuND-2. Grant number AC19/00097).Ye